5-Layer StackThe Clav Protocol
−28.7%Retatrutide Phase 2
11 TotalStack Compounds
>98%HPLC Purity
$200+Free Shipping
The Clav Stack · Clavicular's Protocol · 2026

Clavicular Stack

The Clavicular Stack is a five-layer peptide protocol built around one triple-agonist core and four supporting compounds — Retatrutide for −28.7% body fat, BPC-157 for gut and tissue repair, GHK-Cu and SNAP-8 for skin, and CJC-1295/Ipamorelin for lean mass. Every compound in the Clavicular Stack is documented with its dose, its mechanism and the trial it comes from, and sourced research-grade.

−28.7%
Body weight · Retatrutide Phase 2
5
Protocol layers · Fat · Gut · GLOW · KLOW · Mass
48wk
Phase 2 duration · Weight loss not plateaued
$405
Full stack cost · All 5 layers
The Protocol
Full breakdown →
01
Triple-AgonistGLP-1 · GIP · Glucagon

GLP-3 R — Retatrutide

The engine of the stack. Hits all three receptors — the glucagon agonism is what separates it from tirzepatide. Phase 2 showed −28.7% at 48 weeks. The fat loss core.

02
Gut ProtectionNO-system · gastric mucosal

BPC-157 — Gut Guardrail

GLP-1 agonists hit the gut hard. BPC-157 keeps it intact. 36+ preclinical studies, no minimum toxic dose found. The guardrail on an aggressive Retatrutide protocol.

03
GLOWcollagen · copper peptide · 4,000+ genes

GHK-CU — The GLOW Peptide

Upregulates 4,000+ skin biology genes. Collagen synthesis, VEGF angiogenesis, Cu-SOD antioxidant defense. When you lose 28% body weight, GHK-CU makes the skin show it well.

04
KLOWSNAP-25 NMJ analog · expression wrinkles

SNAP-8 — The KLOW Peptide

SNAP-25 N-terminal analog. Partially inhibits ACh at the NMJ — reducing expression muscle contraction force. Preclinical models: up to 63% wrinkle depth reduction.

05
Lean Massdual GH secretagogue · GHRH + GHRP

CJC-1295 / Ipamorelin — Lean Mass

Pulsatile GH secretagogue combo. Preserves lean mass during aggressive Retatrutide fat loss. No cortisol elevation. Optional layer for those training hard.

Full Stack · 5 Layers

The Protocol

What the
Clavicular Stack
actually is.

The Clavicular Stack is five compounds run together, each doing a job the others cannot. At the centre is Retatrutide, a triple agonist hitting GLP-1, GIP and the glucagon receptor at once — the third of those raises hepatic energy expenditure directly, which is why its Phase 2 readout landed at −28.7% at the high dose over 48 weeks against −20.9% for a dual agonist and −14.9% for a single.

The other four exist because aggressive fat loss costs you things. BPC-157 covers gut and connective tissue while intake is low. CJC-1295 with Ipamorelin works the growth hormone axis so the weight coming off is fat rather than lean mass. GHK-Cu and SNAP-8 handle the skin and collagen side, which is the part people notice first and plan for last.

What makes it a stack rather than a list is the sequencing and the dose ratios between the layers. Run the core alone and you lose weight badly; run all five without the ratios and you are just spending more. Every compound documented here carries the dose it is run at and the trial that dose comes from.

Weight Loss Comparison

Semaglutide
GLP-1 · STEP-1
−14.9%
Tirzepatide
GLP-1 + GIP · SURMOUNT-1
−20.9%
RetatrutideClav's Pick
GLP-1 + GIP + GcgR · Phase 2
−28.7%

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Every compound in Clavicular's protocol in one place. HPLC verified, research grade, ships from the US.