The Clav Protocol: Retatrutide Dose Escalation Reference
The dose escalation schedule from Retatrutide Phase 2 trials, reconstitution guide, and full Clav stack administration reference.
Retatrutide Dose Escalation: The Phase 2 Protocol
All information here is drawn from published Phase 2 trial data and is for laboratory research reference only.
Dose Escalation Schedule
| Phase | Dose | Duration |
| Initiation | 2mg/week | Weeks 1-4 | |||||
| Escalation 1 | 4mg/week | Weeks 5-8 | |||||
| Escalation 2 | 8mg/week | Weeks 9+ | The Phase 2 trial used this three-step escalation to minimize GI side effects during adaptation. Slower escalation is associated with significantly better GI tolerability. Reconstitution Reference | Compound | Vial Size | BAC Water | Concentration |
| Retatrutide | 10mg | 3.3mL | 3mg/mL |
| Retatrutide | 15mg | 5mL | 3mg/mL |
| Retatrutide | 30mg | 10mL | 3mg/mL |
| BPC-157 | 10mg | 10mL | 1mg/mL |
| GHK-CU | 50mg | 10mL | 5mg/mL |
| SNAP-8 | 5mg | 5mL | 1mg/mL |
Reconstitution procedure:
- Let peptide vial reach room temperature
- Clean vial top with alcohol swab
- Inject BAC water slowly along the vial wall (not directly on powder)
- Swirl gently — do NOT shake
- Solution should be clear; if cloudy, do not use
- Label with date and concentration
- Store at 2-8°C
Storage Summary
| State | Storage | Duration |
| Lyophilized powder | Room temp, dark, dry | 12+ months |
| Reconstituted (BAC water) | 2-8°C refrigerator | 4-6 weeks |
BPC-157 Protocol Reference
Running concurrent with Retatrutide from day 1 as GI protection.
All information is for research reference only. Not medical advice.
Shop the Clav Protocol
Research-grade Retatrutide, BPC-157, GHK-CU, SNAP-8 from Apollo Peptide Sciences — every compound in the Clavicular protocol.
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